Tools used in our lab

Immunohistochemistry

A commonly used neuroscience method that allows us to visualize proteins of interest

Immunofluorescence

A method that allows us to visualize proteins of interest using fluorescently labeled antibodies

Behavioral phenotyping

In order to understand the functional consequences of our transgenic manipulations, we use behavioral phenotyping tests that assess cognitive function, depression, and anxiety in mice

Metabolic assays

Using metabolic chambers, we can determine basal metabolic rate (VO2 and VCO2) in transgenic mice exposed to diets that induce obesity

Electrophysiology

We can measure the excitability of neurons using electrophysiology in various parts of the brain such as the hippocampus

Transgenic mouse models

Using mouse models in which genes are either knocked out or overexpressed, we can determine how these different genes ultimately contribute to physiology and brain function

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